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Genetically Modifying Genes and Scientific Evidence

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Altered
Genes, Twisted Truth, by Steven M. Druker

Institute of Science in Society    June 22, 2015

Review of Altered Genes, Twisted Truth, by Steven M. Druker,  Clear River Press, Salt Lake City UT, 2015. ISBN 978-0-9856169-1-5 (hardcover), 978-0-9856169-0-8 (softcover).

Prof Peter Saunders

According to the advocates of genetic engineering, GMOs have been proven by countless rigorous trials to be safe, no humans or even animals have ever been harmed by them, genetic modification is no different from the natural and artificial breeding that has been going on for millennia, it has produced crops with all sorts of desirable properties such as drought resistance, we cannot hope to feed the world without it, and so on.

These statements are all false. And in Altered Genes, Twisted Truth, Steven Druker, a lawyer, shows them to be false exactly as if he were in a courtroom. He has collected a vast amount of documentary evidence: scientific papers and also internal reports and memos. He has interviewed many of the people who were involved and he explains the science so that lay readers can follow the arguments.

The book is a surprisingly good read, considering how long it is and the amount of detail it contains, but it is also a valuable reference text. When the GMO lobby confidently state that genetic engineering is the same as ordinary breeding, this is where you can learn why it is not. When they describe the work of Arpad Pusztai or of Gilles-Eric Séralini as ‘discredited’, you can find out what actually happened, and why neither result has ever been properly challenged, let alone refuted.

It’s not just a matter of one person’s word against another. Unlike the GM lobby, Druker presents solid evidence for what he claims. It’s there in detail and it is fully referenced; you are welcome to check it for yourself.

To give you a flavour of the book, here are brief outlines of two of the early chapters, one on Asilomar and one on tryptophan. Both stories are very important in the history of genetic engineering, but they are seldom mentioned today. When they are, the usual spin is that a few scientists raised their concerns at a meeting but soon accepted that these were unwarranted, and that the tryptophan incident had nothing to do with GM. In both cases, the truth is quite different.

Asilomar

Forty years ago, when transferring genes from one organism to another was first becoming a standard research technique, scientists naturally began to worry about its potential hazards. The US National Academy of Sciences (NAS) appointed a commission to look into the issues, and this led to a letter to the journal Science [1] and then, in February 1975, a meeting of over a hundred scientists at the Asilomar Conference Center in Monterey, California. The outcome was a statement [2] with a list of safety guidelines, including the requirement that research should be carried out using only disabled bacteria that could not survive outside the laboratory. Just the sort of thing you would expect when there is a possibility of danger. Chemists, after all, work in specially designed laboratories, not out in the open, and they have to make special arrangements to dispose of the waste from their experiments; they are not allowed to pour it down the sink and into the public sewers.

The Asilomar guidelines were, however, soon abandoned. They are seldom mentioned today, and if you have heard of them at all you’ve probably been told that while they were an understandable reaction to a new technology, they were soon shown to be unnecessary because it was conclusively demonstrated that the techniques pose no significant hazards.

Druker, who has looked carefully through the published records and interviewed many of those who were around at the time, tells a very different story. One of his key points is that the claim that genetic engineering was safe was largely based on research involving only one bacterium, E. coli K-12. But K-12 had been used in laboratories for many years and was relatively weak, i.e. it would be unlikely to survive outside the laboratory. So while the release of a genetically modified K-12 into the environment might not be dangerous, that would be reassuring only if all future research were confined to K-12. Even then, there would remain the risk that the transferred gene would pass into another, stronger organism.

Yet molecular biologists used, and continue to use, this evidence to justify their claim that genetic engineering involves no special risks and that GM organisms require no more testing than those that have been conventionally bred; they are, in the words of the US Food Additive Amendment of 1958, “generally recognized as safe” (GRAS) and consequently exempted from testing.

It’s easy to understand why so many molecular biologists, rushing to push ahead in what they saw as an important and exciting new area, allowed their enthusiasm to cloud their judgement. They could also see the prospect of turning their research into profit, and that made them even less anxious to think about the dangers. Crucially, they managed to convince the Reagan administration that there was money to be made and jobs to be created and that the US must not be left behind. That, combined with the Reagan-Thatcher policy of relaxing all regulation – in banks as well as in molecular biology – made support for genetic engineering a part of government policy. The US government has consistently backed the GM industry and has used its strength to pressure other countries into accepting GM crops. The Asilomar guidelines and the concerns that led to them have been totally forgotten.

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Fallout from WHO Classification of Glyphosate as Probable Carcinogen

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Fallout from WHO Classification of Glyphosate as Probable Carcinogen

Campaigns to ban and phase out the chemical across the world intensify with major successes

Dr Eva Sirinathsinghji    The Institute of Science in Society     June 10, 2015

Could it be that the World Health Organisation’s classification of glyphosate as a ‘probable carcinogen’ (see [1] Glyphosate ‘Probably Carcinogenic to Humans’ Latest WHO Assessment, SiS 66) will be the final nail in the coffin for the world’s most popular herbicide and Monsanto’s flagship product.

Recent weeks have seen the intensification of campaigns to ban or remove the product as well as lawsuits being filed against Monsanto; in the US for false safety claims of glyphosate, and in China, for hiding toxicity studies from the public. (El Salvador has already banned the chemical though yet to be signed into law [2], while the Netherlands last year banned private sales [3]. Sri Lanka had a partial ban in place in regions most afflicted by chronic kidney disease that has been linked to glyphosate use (see later)).

People have known the truth for years. Industry and government regulators have conspired to bury copious evidence of toxicity for decades, and they feel to some extent vindicated by the latest WHO assessment (see [4] Glyphosate and Cancer, SiS 62) and [5] EU Regulators and Monsanto Exposed for Hiding Glyphosate Toxicity, SiS 51). More importantly, governments are finally beginning to take action.

Outright bans

Colombia has taken the lead, deciding to suspend aerial spraying of illegal coca as well as poppy plants, which is expected to come into effect in a few weeks’ time following a majority 7 to 1 vote for the ban by the National Narcotics Council [6]. The day before the ban, the Interamerican Association for Environmental Defence (AIDA) delivered 24 000 signatures to the Minister of Justice who also chairs the Narcotics Council to push for this decision [7].

Colombia had been employing US contractors to spray glyphosate for two decades, covering an estimated 1.6 million hectares of land. This spraying for the “war on drugs” has been ineffective in eradicating illegal cocaine production, but has instead caused rising illness in local communities, killing local crops and polluting land and water supplies. Indigenous and Afro-Colombian communities have borne the brunt of the fumigation programs, prompting protests against both coca production and glyphosate use that has been displacing people from ancestral lands [8]. Colombia is not alone.

Bermuda, the British overseas territory in the Atlantic also banned glyphosate imports with immediate effect following the WHO assessment, as announced by their Minister of Health, Jeanne Atherden, whose decision was supported by local farmers [9]. The Minister said she believes the “action we are taking today is prudent and in the best interests of a safe environment….Like any area of science, there are competing studies and a wealth of information on both sides of the argument….  I am satisfied that this action is warranted and we are committed to conducting an open and thorough investigation” [10].

Sri Lanka is the latest country to declare an outright ban. The decision follows the election of the new president, a farmer and previously the Health Minister, Maithripala Sirisena taking the decision due the epidemic of chronic kidney disease [11].The spread of kidney disease highlights the wide-ranging toxicity of glyphosate not limited to carcinogenicity. The country’s battle to ban the chemical precedes the WHO declaration, coming after studies by Sri Lankan researchers linked the chemical to hard water, heavy metal contaminants and glyphosate use (see [12] Sri Lanka Partially Bans Glyphosate for Deadly Kidney Disease Epidemic, SiS 62). This prompted an initial ban, which was later restricted to certain regions of the country following intense lobbying pressure. With the government paying for healthcare of over 25 000 residents and supplying them with fresh water, the latest decision for an outright ban could not come soon enough.

Imminent bans, protests, and fresh calls for bans

Brazil is facing growing pressure to follow suit, with the country’s public state prosecutor writing to Brazil’s National Health Surveillance Agency (ANVISA) asking it to urgently re-evaluate their stance on glyphosate and also revoke authorisations on glyphosate-tolerant GM crops [13]. He has even gone as far as launching an investigation into whether regulatory authorisations are legal for the GM crops. ANVISA are stalling their decision however, until the full report by the WHO is published.

In Argentina, 30 000 health professionals belonging to the union of doctors and health professionals (FESPROSA) have come out in support of the WHO decision [14], claiming that glyphosate “not only causes cancer. It is also associated with increased spontaneous abortions, birth defects, skin diseases, and respiratory and neurological disease.” The statement continues: “Health authorities, including the National Ministry of Health and the political powers, can no longer look away. Agribusiness cannot keep growing at the expense of the health of the Argentine people. The 30,000 health professionals in Argentina in the FESPROSA ask that glyphosate is now prohibited in our country and that a debate on the necessary restructuring of agribusiness is opened, focusing on the application of technologies that do not endanger human life.”

Similarly, the Society of Paediatric Haematology-Oncology (SAHOP) issued a statement calling for an immediate ban of glyphosate fumigation, signed by the President of the Paediatric society Pedro Zubizarreta.  They objected to the massive use of toxic products being sprayed in ever increasing concentrations in combinations of both insecticides and herbicides, and being sold as ‘technological advancements’. They also warned of storing the grains in plastic bags, which leaves grains teeming with aflatoxins, categorised by the WHO’s IARC as a known carcinogen since 1993 [15]. Glyphosate has already been previously linked to the growth of these fungi in scientific studies, along with many other crop diseases [16].

Successful protests in Argentina were also recently mobilised to prevent Dr Medardo Ávila Vázquez from losing his job after the agribusiness-funded university threatened to sanction him for conducting and disseminating studies showing the high levels of cancers affecting his region as a result of agrichemical spraying [17]. These protests are a tribute to his work in exposing the toxicity of glyphosate, as well as the groundswell of opposition to glyphosate spraying in the country despite support by the national government. Local residents are gaining strength to voice their concerns following the WHO news as well as the recent decision by the Ministry of Production in the province of Santa Fe to ban aerial spraying of 2,4-D within 6 km of residents, confirming the health risks of the chemical agricultural system that leaves children covered in chemical and dust particles as they walk to school [18].

In Europe, the International Society of Doctors for the Environment (ISDE) (an influential body with member organizations in 27 countries) has written to officials at the EU parliament and Commission asking for an immediate ban of glyphosate herbicides and for insecticides also judged by the WHO to be carcinogens, without exceptions [19]. A member of the EU commission stated in the 2015 GMO-free conference 2015 in Berlin, Germany that they will include the WHO assessment in their re-evaluation procedures that is due to be completed later this year. However the corrupt process of reassessment that was led by a consortium of chemical companies (see [20] Scandal of Glyphosate Re-assessment in Europe, SiS 63) means that EU campaigners will have to push hard to force the EU to have some semblance of integrity in their final decision making.

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U.S. No Longer An Actual Democracy- Princeton Study

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Princeton Study: U.S. No Longer An Actual Democracy

By Brendan James  April 18, 2014    TPM

A new study from Princeton spells bad news for American democracy—namely, that it no longer exists.

Asking “[w]ho really rules?” researchers Martin Gilens and Benjamin I. Page argue that over the past few decades America’s political system has slowly transformed from a democracy into an oligarchy, where wealthy elites wield most power.

Using data drawn from over 1,800 different policy initiatives from 1981 to 2002, the two conclude that rich, well-connected individuals on the political scene now steer the direction of the country, regardless of or even against the will of the majority of voters.

TPM Interview: Scholar Behind Viral ‘Oligarchy’ Study Tells You What It Means
“The central point that emerges from our research is that economic elites and organized groups representing business interests have substantial independent impacts on U.S. government policy,” they write, “while mass-based interest groups and average citizens have little or no independent influence.”

As one illustration, Gilens and Page compare the political preferences of Americans at the 50th income percentile to preferences of Americans at the 90th percentile as well as major lobbying or business groups. They find that the government—whether Republican or Democratic—more often follows the preferences of the latter group rather than the first.

The researches note that this is not a new development caused by, say, recent Supreme Court decisions allowing more money in politics, such as Citizens United or this month’s ruling on McCutcheon v. FEC. As the data stretching back to the 1980s suggests, this has been a long term trend, and is therefore harder for most people to perceive, let alone reverse.

“Ordinary citizens,” they write, “might often be observed to ‘win’ (that is, to get their preferred policy outcomes) even if they had no independent effect whatsoever on policy making, if elites (with whom they often agree) actually prevail.”

Global Assault on Seed Sovereignty through Trade Deals

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Global Assault on Seed Sovereignty through Trade Deals Is Assault on Human Rights, Protest is Fertile

From Asia to South America, the EU to the Caribbean, the corporate seed industry is using international trade agreements to criminalise farmers for saving seeds

(A fully referenced version of this report is posted on ISIS members website and otherwise available for download here)   Institute of Science in Society     01/12/15

Dr Eva Sirinathsinghji

The multinational seed industry is continuing its multipronged attack on the most basic of human rights, the access to seed. Lobbyists of the seed industry are using trade agreements to pressure nations into adopting strict measures such as UPOV agreements that ensure the protection and ownership of new plant varieties for plant breeders. On top of this, corporate seed industry lobbyists are proposing revisions to the UPOV convention that promote further monopolisation of the seed industry through ‘harmonisation’ of procedures for registering and testing new plant varieties.

Protests in many regions around the world are putting up much needed resistance against this corporate takeover of the food system, successfully forcing governments to delay and even repeal the agreements. These movements are an inspiration for our continual global struggle against the relentless onslaught of agribusiness whose current biggest targets are the ‘untapped’ markets of the global South, with the spotlight on Africa and other regions where seeds have not yet been commercialized, and are still used in traditional systems that allow seed saving and exchange.  Read the rest of this entry »

2014: The Year Propaganda Came Of Age

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Meijer sums it all up very well (read the whole thing!)

2014: The Year Propaganda Came Of Age

   December 26, 2014    by

……that truly defines 2014 for me. A level of propaganda I don’t recognize, and I don’t think I’ve ever seen before. 2014 has for me been the year of utter nonsense. To wit, it just finished in fine form with a 5% US GDP growth number, just to name one example. Really, guys? 5%? Really? With all the numbers presented lately, the negative Thanksgiving sales data – minus 11% from what I remember -, the so-so at best Christmas store numbers to date, shrinking durable goods in November and all? Plus 5%?

It really doesn’t matter what I say, does it? You have enough people believing ridiculous numbers like that to make it worth your while. After all, that’s all that counts…..

…..Ukraine defines 2014 as the year western propaganda came into its own. Not just fictional stories about an economic recovery anymore, no, we had our politico-media establishment ram an entire new cold war down our throats. And we swallowed it whole. We may have had a million more years of higher education than our parents and grandparents, but we sure don’t seem to have gotten any smarter than them……

 read entire article here

Congressional report: Did Certain Foreign Governments Facilitate 9/11 ?

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A Congressional report titled “Finding, Discussion and Narrative Regarding Certain Sensitive National Security Matters” … has gotten zip coverage by the media. This report can be read only by heads of Senate and House intelligence committees and, with their permission, by Members of Congress who are carefully guarded and not allowed to take notes.

Friday, August 29, 2014 INFORMATION CLEARING HOUSE (ICH)

Did Certain Foreign Governments Facilitate the 9/11 Attacks?

By JUSTIN RAIMONDO
…….”One or more foreign governments,” eh? Who in the Middle East – or anywhere else, for that matter – are among “those whom we thought we could trust”? That doesn’t sound like the Saudis to me. Would anyone really be surprised or “disappointed” to learn that they were playing games behind our back?

[Kentucky’s 4th district] Rep. Thomas Massie’s statement is even more revealing: “I had to stop every two or three pages and rearrange my perception of history. And it’s that fundamental – those 28 pages ….It certainly changes your view of the Middle East.”…

read entire article here
 
 

Hilarious Monsanto/Condé Nast Meltdown (UPDATED)

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Last week, Gawker uncovered a hapless tie-up between genetically modified seed/pesticide giant Monsanto and Condé Nast Media—publisher of The New Yorker, Bon Appetit, GQ, Self, Details, and other magazines—to produce “an exciting video series” on the “topics of food, food chains and sustainability.”

Marion Nestle was offered $5,000 to participate for a single afternoon.

Since then, I’ve learned that Condé Nast’s Strategic Partnerships division dangled cash before several high-profile food politics writers, in an unsuccessful attempt to convince them to participate.

Marion Nestle, author of the classic book Food Politics and a professor at New York University, told me she was offered $5,000 to participate for a single afternoon. Nestle almost accepted, because at first she didn’t know Monsanto was involved—the initial email she received only referred to the company in attachments that she didn’t open, she said.

“It wasn’t until we were at the end of the discussion about how much time I would allow (they wanted a full day) that they mentioned the honorarium,” she wrote in an email. “I was so shocked at the amount that I had sense enough to ask who was paying for it. Monsanto. End of discussion.”  …..read entire article here

Israeli Intelligence Eavesdropped on Kerry’s Phone During Gaza Peace Talks

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I am the first English language publication to report his major story.  Der Spiegel publishes in today’s edition that Israeli intelligence (likely Unit 8200) eavesdropped on phone calls John Kerry made to his Palestinian interlocutors during the peace talks he conducted for the past year.  Though Kerry usually talked on encrypted phone lines from his State Department office or Georgetown home, when he was in flight to or from the region he had to use a satellite phone, which was not encrypted.  This allowed the Israelis to listen in on everything he said to the Palestinians.  It allowed them to know what ideas he was floating and prepared for them to counter them in the negotiation process.  When the Israelis really disliked a proposal they knew better how to attack it before Kerry had even brought the subject up….. entire article here

28 years have passed since the EPA’s last chemical risk review

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Tens of thousands of chemicals have not been reviewed by the EPA, and people are starting to ask questions

This week, the Environmental Protection Agency (EPA) hit a major milestone that some people, including leaders at the agency itself, think shouldn’t be celebrated.

On Wednesday, the agency released a final risk assessment for trichloroethylene (TCE), an industrial solvent used by artists, car mechanics, dry cleaners and others. The EPA’s in-depth report, released after a two-year analysis, shows that long-term exposure to TCE can cause cancer and other health issues, and recommends that workers take serious precautions if they must use TCE.

But in its press release, the EPA acknowledged there was something wrong — not with the risk assessment itself — but with its timeline: It was the first final risk assessment for a chemical issued by the EPA since 1986.

“The American public shouldn’t have to wait 28 years between … chemical risk assessments,” wrote Jim Jones, EPA assistant administrator of chemical safety….. read full article here

Hazards of GMOs: Nucleic Acid Invaders from Food Confirmed

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Dr Mae-Wan Ho  Institute of Science in Society  June 11, 3014

New research confirms that DNA fragments derived from meals, large enough to carry complete genes, can escape degradation and enter the human circulatory system, and so can RNA, raising serious concerns over new nucleic acids introduced into the human food chain via genetically modified organisms.

Food RNA gets into blood and so does DNA

We have alerted readers to research showing how tiny RNA molecules in food eaten can circulate in the bloodstream and turn genes off in the body [1], raising concerns over the safety of genetically modified organisms (GMOs), which introduce many novel and synthetic nucleic acids into the human food chain ([2] How Food Affects Genes, SiS 53). New research shows that pieces of DNA large enough to code for complete genes can also escape degradation in the gut and enter the human circulatory system, and the presence of circulating RNA from food is much more extensive and widespread. Read the rest of this entry »