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Roundup®: Converging Pattern of Toxicity from Farm to Clinic to Laboratory Studies

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roundup toxic

A Roundup of Roundup® Reveals Converging Pattern of Toxicity from Farm to Clinic to Laboratory Studies

We need to ban glyphosate from our own communities as most governments fail to protect citizens

Institute of Science in Society   1/19/15

**please support research of Seralini’s team on analysing glyphosate residues in rats exposed to Roundup here: http://www.i-sis.org.uk/Support_Seralini_Team_for_New_GMO_Risk_Research.php

Dr Eva Sirinathsinghji

What is glyphosate?

Glyphosate, perhaps surprisingly for a chemical so ubiquitously associated with our food, was not first used as an agricultural chemical but instead first patented as a metal chelator in 1964 by Stauffer Chemical company (US 3160632 A) [1] and used as an industrial pipe cleaner. It was later patented by Monsanto as an herbicidal agent in 1974 (US3799758 A) [2] based on its ability to block the shikimate pathway involved in the production of aromatic amino acids in both plants and bacteria. It has become the most popular herbicide in the world especially since glyphosate tolerant genetically modified (GM) crops were commercialized in the mid-1990s, together with the assumption (perpetrated by Monsanto) that the herbicide is safe for health and the environment. In 2010, it was also patented by Monsanto as an antibiotic agent. Moreover, it is being increasingly used as a pre-harvest desiccant for drying seeds, a process that results in contamination of non-GM grains, one of the main exposure routes in the EU where GM crops are not commonly grown. Thus, an estimated 70 % of UK oil seed rape (canola) and 50-60 % of EU sunflowers are sprayed with glyphosate [3], resulting in products of major food brands in the UK testing positive for glyphosate residues in a 2014 analysis by GM Freeze, with glyphosate the most commonly detected of all chemicals [4].

All of glyphosate’s chemical properties already mentioned have implications for the health of both people and planet. Scientific research has additionally implicated glyphosate as an endocrine disruptor and a DNA mutagen; and it affects over 291 different enzymes in the body [5]. It is increasingly linked with a wide variety of illnesses, the sharp rises in illnesses occurring in parallel with glyphosate application across various GM cultivating regions of the world.

The most convincing evidence of glyphosate toxicity is the consistent pattern of diseases associated with glyphosate that has emerged from the farm to the clinic and from scientific studies to citizen testimonials.

Glyphosate widespread in the environment and in our bodies

Glyphosate’s popularity is due in large measure to its concomitant use with the most widely planted type of GM crops, those tolerant to glyphosate-herbicides. Monsanto commercialised the first Roundup-ready crop in 1996 (Roundup being the commercial formulation containing ‘adjuvants’ that make it much more toxic than the active ingredient glyphosate alone, see later). In countries such as Argentina where large swaths of the country have been dubbed soy deserts, GM soybean cultivation has resulted in an 858 % rise in glyphosate use (see [6] Devastating Impacts of Glyphosate Use with GMO Seeds in Argentina, to appear). Similarly, the US has seen even greater rises of 2 500 % from 1987 to 2007 [7].

This widespread and massive application of glyphosate herbicides has resulted in almost ubiquitous contamination of the environment. A 2014 study on US water systems across 38 states found glyphosate and its principle metabolite AMPA (aminomethylphosphonic acid) not only in rivers, lakes and streams, but also rain, soil and sediment, ditches and drains and groundwater (see [7]). Some 70 % of rain samples tested positive for glyphosate. Similarly in Europe, (in Catalonia, a large region of Spain) it was found that all 11 groundwater sites were positive for glyphosate despite it being a region free from glyphosate-tolerant crop cultivation; 41 % of samples were above detection limits [8]. The detection in groundwater goes against one of the claims on glyphosate safety that its propensity to bind to soil and sediment means it will not leach into our fresh water supplies. In Argentina, new data of rain sample measurements averaged an extreme 6.5 µg/L and reaching as high as 67 µg/L (67 ppt) across four regions from October 2012 to April 2014 [9]. These levels are far higher than those seen in US rain samples where the average and maximum concentrations were 0.11 µg/L and 2.5 µg/L respectively [7]. Read the rest of this entry »

Chem Corps mega $$ donations to defeat GMO labeling: time to fight back!

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Updated below

DuPont’s massive donation of $4.46 million this week, shattered the record for making the single largest contribution to a political campaign in Oregon history!

  • DuPont – the giant chemical corporation – dumped a whopping $7.46 MILLION into the GMO labeling fight this week – $4.46 million in Oregon and $3 million in Colorado!
  • Already Monsanto has spent more than $8.1 million in Oregon and Colorado to prevent common sense labeling initiatives from being passed into law.
  • These companies – combined with Coca-Cola, PepsiCo, and the rest of their agrochemical friends – have spent a whopping $30+ MILLION to defeat GMO labeling.

That’s right, these 5 corporations are leading the pack to deceive voters by dumping in a stunning $30 MILLION to silence our voices and keep GMOs unlabeled on our tables. In Oregon, Monsanto, DuPont and Friends have already dumped more than $16.5 million to defeat Measure 92, while pouring another $14.3 million to defeat of Colorado’s Prop 105.

The real question is – What are they so desperate to HIDE?

We saw this in Washington in 2013 and California in 2012 – Monsanto, DuPont and the rest of their Big Food friends will stop at absolutely nothing in their disinformation campaign to defeat GMO labeling. They’ll lie to and confuse voters in misleading TV ads airing every single day if it means preventing GMO labeling from becoming law.

We can’t let them win! A victory at the ballot boxes for labeling would be a historic moment for our GMO labeling movement. We could see a wave of similar labeling measures roll across the entire nation – but only if we’re able to fight back now and deliver a crushing blow to Monsanto.

You could be the deciding factor in defeating Monsanto and winning GMO labeling. Make an urgent contribution today and we’ll rush it directly to labeling supporters in Colorado and Oregon.

What your contribution today will help accomplish:

  • Chip in $25 today to support volunteers going door to door in neighborhoods across Oregon and Colorado.
  • Chip in $50 today to buy 70 mailers to get the message out to voters. With the 3 to 1 match this will reach 210 voters!
  • Chip in $100 today to support volunteer phone banks to make more than 500 calls! With the triple match this grows to 1,500 phone calls to targeted voters!
  • Chip in $250 today to reach 400,000 voters with a hard-hitting TV ad!
  • Chip in $500 today to reach 1 million voters to combat the lies of Monsanto and the GMA’s misleading ads.

We’re running out of time to fight for GMO labeling in Colorado and Oregon. Standing up to the huge chemical companies will take everything we’ve got – are you in?

Please don’t wait – contribute before midnight tonight and your donation will be triple-matched by the incredible teams at Presence Marketing and Dr. Bronner’s Magic Soaps.

TRIPLE your impact before time runs out – we need to hear from you today! Every dollar counts!

Update 11/21/14:

GMO labeling measure heads into recount range as opposition margin narrows dramatically

Hilarious Monsanto/Condé Nast Meltdown (UPDATED)

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Last week, Gawker uncovered a hapless tie-up between genetically modified seed/pesticide giant Monsanto and Condé Nast Media—publisher of The New Yorker, Bon Appetit, GQ, Self, Details, and other magazines—to produce “an exciting video series” on the “topics of food, food chains and sustainability.”

Marion Nestle was offered $5,000 to participate for a single afternoon.

Since then, I’ve learned that Condé Nast’s Strategic Partnerships division dangled cash before several high-profile food politics writers, in an unsuccessful attempt to convince them to participate.

Marion Nestle, author of the classic book Food Politics and a professor at New York University, told me she was offered $5,000 to participate for a single afternoon. Nestle almost accepted, because at first she didn’t know Monsanto was involved—the initial email she received only referred to the company in attachments that she didn’t open, she said.

“It wasn’t until we were at the end of the discussion about how much time I would allow (they wanted a full day) that they mentioned the honorarium,” she wrote in an email. “I was so shocked at the amount that I had sense enough to ask who was paying for it. Monsanto. End of discussion.”  …..read entire article here

Sri Lanka Partially Bans Glyphosate for Deadly Kidney Disease Epidemic

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04/09/14  The Institute of Science in Society      roundup kills

Glyphosate’s metal-chelating activity causes bioaccumulation of toxic metals in the body, resulting in an estimated 400 000 cases in Sri Lanka and 20 000 deaths     Dr Eva Sirinathsinghji

Sri Lanka is set to partially ban glyphosate-based herbicide use following a new peer-reviewed study linking it to a fatal chronic kidney disease epidemic badly affecting the country [1]. Kidney problems have been further documented in other global regions, prompting an earlier complete ban by El Salvador late last year [2]. A complete ban was initially proposed, but due to plantation sector representatives claiming a shortage of agricultural workers that would not sufficiently manage weeds without glyphosate, the government has now limited the ban to disease endemic areas [3]. Even Brazil, one of the largest growers of glyphosate-tolerant genetically modified (GM) crops has now filed a law suit by Federal Prosecutors to ban glyphosate along with 8 other dangerous pesticides [4]. It is becoming increasingly difficult for government regulators and glyphosate producers to justify the use of this herbicide when other nations are banning the chemical outright in order to protect their citizens.

Glyphosate can impact human health in a number of ways, one of which is through its potent metal chelating abilities. Indeed, glyphosate was originally patented by Stauffer Chemical Co. in 1964 (U.S. Patent No. 3,160,632) [5] for this very function. Chelating mineral ions can lead to nutritional depletion in plants and animals, which has already been shown to cause health problems in both. In the case of this kidney disease epidemic, its chelation of metals such as arsenic in the water supplies is now though to lead to their bioaccumulation in the body, resulting in kidney failure and even death, as proposed in a new study [6] by Channa Jayasumana (Rajarata University, Sri Lanka), Sarath Gunatilake (California State University, USA) and Priyantha Senanayake (Hela Suwaya Organization, Sri Lanka) published in the International Journal of Environmental Research and Public Health. Glyphosate has also been linked to many other health problems including cancers (see [7] Glyphosate and Cancer, SiS 62), infertility (see [8] Glyphosate/Roundup & Human Male Infertility, SiS 62), along with neurotoxicity, reproductive problems, birth defects, and other problems (see [9] Ban GMOs Now, special ISIS report). Read the rest of this entry »

Written by laudyms

April 9, 2014 at 8:41 am

Colombian Farmers Defeat Monsanto: Win Back Control of Seeds

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Sept. 17, 2013  By Oscar León The Real News – reposted at Food Freedom News

Colombians in Trafalgar Square show their support for the farmers' strike in Colombia. Protesters are demonstrating against the free trade agreement with the US; seed multinationals; GMO crops, and seed patents. Photo by Andres Pantoja

Colombians in Trafalgar Square show their support for the farmers’ strike in Colombia. Protesters are demonstrating against the free trade agreement with the US; seed multinationals; GMO crops, and seed patents. Photo by Andres Pantoja

On Sept. 10 in Colombia, after 21 days of a nationwide strike by thousands of farmers, who were supported by bus and truck drivers, miners, students, and others joining massive demonstrations in cities and towns all around the country in places as far as Boyacá, Cundinamarca, Cauca, Huila, Putumayo, Caldas, Cundinamarca, and Nariño, and blocking more than 40 roads, in an historic moment, protesting farmers forced the Colombian government to negotiate the rejection of a farm bill and the release of detained protesters.

On Sunday, September 8, Vice President Angelino Garzón met with the Strike Negotiating Commission in Popayan and agreed to suspend Law 970, the one that gave control over seeds to the government [which made it illegal for farmers to save seeds, any seeds, forcing them to buy patented ones].

They also were promised the release of the 648 arrested during the strike and the creation of a new mining law.

Under this first and provisional agreement, the government will compensate the farmers for their losses when competing with cheaper products imported under as much as ten free market treaties with countries all around the world. In other cases it will suspend the importation of such products.

The strike was ended and negotiations started to discuss the farmers’ proposals. The process of negotiation, as well as the final agreement and its implementation, will be verified by the United Nations.

Read the rest of this entry »

Industry and regulators covered up Roundup/birth defect link for decades

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July, 2011            ResponsibleTechnology.org

The pesticide industry knew from its own studies (including one by Monsanto) as long ago as the 1980s-and EU regulators knew since the 1990s- that the best-selling herbicide Roundup causes birth defects.

A new report by international scientists now exposes the 30-year cover-up, including efforts as recent as last year by the German government’s consumer protection office to rebut a 2010 study showing Roundup causes birth defects in frogs and chickens at tiny doses. The study was prompted by reports of high rates of birth defects and cancers in areas of South America growing GM Roundup Ready soy, which is sprayed with high doses of the herbicide. Read a lengthy article on this in the Huffington Post, a summary in The Ecologist, or the full report “Roundup and birth defects: Is the public being kept in the dark?” Monsanto responded to the report, but the report’s authors pick apart the company’s statements, showing how they are unsupported and unscientific.

Monsanto is Poisoning Us All: Famous Scientist, Don Huber Exposes Hazards of Monsanto’s Roundup Herbicide

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Update:  Watch Food Democracy Now’s interview with Dr. Huber

originally published as: Latter-Day Luther Nails Troubling Thesis to GM Farm & Food Citadels ,

March 29, 2011  by Steven McFadden

Don M. Huber, Ph.D.

After trucking across the high plains for five hours, and casting my eyes over perhaps 100,000 acres or more of winter’s still deathly gray industrial farmland, I came face to face with the newly famous Dr. Don M. Huber in the cave-dark meeting room of the Black Horse Inn just outside the American Heartland village of Creighton, Nebraska.

On the morning of March 24, along with about 80 farmers and Extension agents, I listened as Huber discoursed with erudition and eloquence upon industrial farming practices that may be impacting nearly every morsel of food produced on the planet, and that subsequently may also be having staggeringly serious health consequences for plants, animals, and human beings.

Huber is emeritus soil scientist of Purdue University, and a retired U.S. Army Colonel who served as an intelligence analyst, for 41 years, active and reserves. In Nebraska, he stood ramrod straight for three hours with no notes and spoke with an astonishing depth and range of knowledge on crucial, controversial matters of soil science, genetic engineering, and the profound impact of the widely used herbicide glyphosate upon soil and plants, and ultimately upon the health of animals and human beings.

Dressed in a conservative dark suit and tie, Huber set the stage for his presentation by observing that he has been married for 52 years, and has 11 children, 36 grandchildren, and a great-grandchild on the way. He then began his formal talk framed by a PowerPoint slide bearing a Biblical quote: “All flesh is grass.” – Isaiah 4:6. With this he emphasized the foundational reality that the biotech grains we eat, as well as the biotech grains eaten by cows, hogs, and chickens, are grown in vast herbicide-treated fields.

Martin Luther nails his theses to the church door.

For the domineering giants of industrial agriculture — multinational corporations, universities, and governments — Huber’s assertions about the impact of glyphosate, and the mounting scientific questions about GMO crops, may be as significant and disrupting as Martin Luther’s “heretical” act in 1517. That’s when Luther nailed his 95 theses to the door of the Castle Church in Wittenberg, Germany to challenge the systemic problems in the almighty institutions of his era.

Luther disputed the claim that spiritual forgiveness from sins could be legitimately sold for money. Huber and other researchers say they are accumulating evidence that — along with the 2010 report of the U.S. President’s Cancer panel which bluntly blames chemicals for the staggering prevalence of cancers — raises profoundly challenging questions about the chemical and genetic-engineering practices of industrial agriculture. The challenge, if it holds up, has implications not just for agricultural institutions, but also for the primary food chain serving the Earth’s population.

Not an altogether new controversy, the complex matters of industrial agriculture, genetic engineering and the far-flung use of herbicides has been ominously and exponentially accentuated in the last year by virtue of its ominous context: last summer’s epic oil catastrophe in the Gulf of Mexico, the nation-ripping 9.0 earthquake in Japan earlier this month, with its subsequent tsunami and nuclear meltdown which is contaminating the nation’s water and food chain, in combination with the statistical reality that on our planet of nearly seven billion people, over a billion human beings — one of every six of us — is hungry.

All of this was brought into prominent public focus — both sharp and fuzzy — in January of this year by the unlikely matter of alfalfa.

Read the rest of this entry »

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